7 edition of The cancer degradome found in the catalog.
Includes bibliographical references and index.
|Other titles||Proteases and cancer biology|
|Contributions||Edwards, Dylan R.|
|LC Classifications||QP609.P78 C36 2008|
|The Physical Object|
|Pagination||xxiii, 926 p.,  p. of plates :|
|Number of Pages||926|
|LC Control Number||2008928134|
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"The Cancer Degradome: Proteases in Cancer Biology", edited by Dylan Edwards, Francesco Blasi, Gunilla-Høyer-Hansen and Bonnie Sloane, covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how protease activity can be imaged both in vitro and.
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This book will aim to cover recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; how their activity can be imaged both in vitro and in vivo; the links that have emerged between proteolysis and cell signalling; how.
The last decade has witnessed a revolution in our thinking concerning the role of extracellular proteolysis in cancer biology: this is the primary focus of this book.
The cancer degradome: Proteases and cancer biology. Book January the term cancer degradome defines the set of protease genes expressed by a tumour at a. The ailments and conditions that afflict people today can be confusing, disturbing, and painful—both emotionally and physically.
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Degradomics is a sub-discipline of biology encompassing all the genomic and proteomic approaches devoted to the study of proteases, their inhibitors, and their substrates on a system-wide scale.
This includes the analysis of the protease and protease-substrate repertoires, also called "protease degradomes". The scope of these degradomes can range from cell, tissue, and organism-wide scales.
Cancer is the second leading cause of death in the United States. Lung cancer is the leading cause of cancer death in adults; leukemia is the most common cancer in children. Other common types of cancer include breast cancer (in women), prostate cancer (in men), and colon cancer (see also Hodgkin's disease).
The incidence of particular cancers. Every human being has cancer cells in their body. Most people don’t even know they have cancer cells because their immune system safely and easily kills their cancer cells as they form.
In fact, as long as there is a balance between the number of new cancer cells in their body, and the strength of [ ]. The cancer degradome proteases and cancer biology Saved in: Restrictions on access to electronic version: access available to SOAS staff and students only, using SOAS id and password.
The book on Lung Cancer was launched in the 3rd Asian Single Port VATS Symposium & Liver Surgery with the recognition of the world known experts (from right to left): Prof.
Alan Sihoe, Prof. Jianxing He, Prof. Jheon Sanghoon, Prof. Thomas D’Amico.Matrix remodeling proteases, including metalloproteinases, serine proteases, and cysteine cathepsins, have emerged as important regulators of cancer development due to the realization that many provide a significant protumor advantage to developing neoplasms through their ability to modulate extracellular matrix metabolism, bioavailability of growth and proangiogenic factors, regulation of Cited by: 1.